Symbol
Name
ID

Trp53bp1
transformation related protein 53 binding protein 1
MGI:1351320

Phenotype annotations related to immune system

Darker colors indicate more annotations

Mouse Phenotypes

small thymus

thymus hypoplasia

abnormal class switch recombination

abnormal T cell differentiation

increased double-negative T cell number

decreased mature B cell number

decreased B cell number

increased central memory CD4-positive, alpha-beta T cell number

decreased CD4-positive, alpha-beta T cell number

decreased CD8-positive, naive alpha-beta T cell number

decreased T cell number

decreased IgD level

decreased IgG level

impaired humoral immune response

Availability

Mouse Genotype

Trp53bp1^{Gt(OST94324)Lex}/Trp53bp1^{Gt(OST94324)Lex}

Trp53bp1^m2Btlr/Trp53bp1^m2Btlr

Trp53bp1^m3Btlr/Trp53bp1^m3Btlr

Trp53bp1^m4Btlr/Trp53bp1^m4Btlr

Trp53bp1^m5Btlr/Trp53bp1^m5Btlr

Trp53bp1^tm1Jc/Trp53bp1^tm1Jc

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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